Will Septerna stock go up?

According to Danelfin AI, Septerna has today an AI Score of 7/10 (Buy rating), because its probability of beating the market in 3 months (60.00%) is +9.18% vs. the average probability (50.82%) of all US-listed stocks.

What is the target price for Septerna stock?

The Septerna target price is $42.46 (1Y), according to the average price target offered by analysts.

Is it a good time to buy, sell, or hold Septerna stock right now?

Septerna has today a Buy rating (AI Score 7/10), according to Danelfin AI. Its probability of beating the market in 3 months (60.00%) is +9.18% vs. the average probability (50.82%) of all US-listed stocks, based on our AI-powered analysis. You can find more details on whether Septerna stock is a good buy .

Is Septerna undervalued right now?

Based on analysts, the average price target upside for Septerna is +22.60% (1Y). According to Danelfin AI, Septerna has today an AI Score of 7/10 (Buy Rating).

What was the price range of Septerna stock over the past 12 months?

The Septerna stock price range over the past 12 months has been $10.47 - $37.34.

What is going on with Septerna stock in the last 3 months?

The Septerna stock performance in the last quarter has been +44.11%.

Does Septerna offer dividend payments?

No, Septerna does not currently pay dividends.

What is the current market capitalization of Septerna?

Septerna's market cap is $1.56B, as of 2026-07-02 08:00.

When is the next SEPN earnings report date?

SEPN will publish its next earnings report on 2026-05-11.

Septerna Inc (SEPN) AI Stock Analysis

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SEPN AI-Powered Stock Analysis

AI Score Explanation

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Valuation+4.96%
How the stock is priced relative to its fundamentals
Sentiment+2.59%
How analysts and the market view the stock
Momentum+1.84%
Direction and strength of recent price movements
Earnings Quality+1.73%
Stability and reliability of reported earnings
Growth+0.64%
Expected pace of revenue and earnings expansion
Size & Liquidity+0.47%
Company size and trading liquidity

Volatility-1.84%
How much the stock price tends to fluctuate
Profitability-1.20%
Profitability and operating efficiency metrics

SEPN probability advantage of beating the market (3M):

+9.18%

AI Score

Buy

Septerna (SEPN) has an AI Score of 7/10 (Buy) because, according to an overall analysis, it has a probability advantage of +9.18% of beating the market (S&P500) in the next 3 months. This advantage is calculated as the difference between the average probability of any US-listed stock (50.82%) and the probability of SEPN (60.00%) of outperforming the market in the next 3 months, as determined by Danelfin AI’s comprehensive analysis.

Average probability of any US-listed stock of beating the market (3M)50.82%
SEPN probability advantage of beating the market (3M)+9.18%
SEPN probability of beating the market (3M)60.00%

SEPN probability advantage of beating the market (3M): +9.18%

The AI-powered overall analysis of Septerna (SEPN) is based on the 27 fundamental, technical, and sentiment features that had the greatest impact on stock performance during the last 12 months (alpha signals). These alpha signals explain the probability advantage of SEPN:

Type	Alpha Signal	Current Value	Value Decile Position	Probability Advantage Impact (3M)
Fundamental	Fundamentals Impact (Long Tail)	-	N/A	+4.05%
Sentiment	Industry (GICS)	Pharmaceuticals	N/A	+2.59%
Fundamental	Operating Cash Flow (Qtr Discrete)	-25.63		+1.73%
Technical	Technicals Impact (Long Tail)	-	N/A	+1.65%
Technical	Chart Pattern (252d)	figure_78	N/A	+1.31%
Sentiment	Fear & Greed Index (CNN)	31	N/A	-1.12%
Technical	Maximum Volatility	7.78%		-0.83%
Fundamental	Gross Margin	100		-0.75%
Fundamental	Cash per Share (MRQ)	7.71		+0.68%
Technical	Chart Pattern (180d)	figure_193	N/A	-0.68%
Sentiment	Upgrade to unlock			+0.64%
Fundamental	Upgrade to unlock			+0.60%
Technical	Upgrade to unlock			-0.60%
Technical	Upgrade to unlock			+0.51%
Sentiment	Upgrade to unlock			+0.48%

Rest of Alpha Signals: -1.08%

SEPN probability advantage of beating the market (3M)Total:+9.18%
SEPN AI Score

Significant changes Vs previous day

SEPN Trading Parameters

These suggested trading parameters for a 3-month horizon help improve risk management and decision-making.

Entry:$34.63
Horizon: 3 months
Stop Loss:$XXXXXPro (XXXXXPro) or AI Score < 7/10
Take Profit:$XXXXXPro (XXXXX
Pro
) or AI Score < 7/10

SEPN Proven Buy Signal & Price Forecast

This is the price chart for SEPN from January 1, 2026 until today. The chart indicates, in green, the 52 days when the stock received a Buy/Strong Buy rating (buy signals, AI Score 7 to 10).

Forecast: In the section below, the central dotted line represents the most expected path, while the shaded area indicates the anticipated price range. This is based on previous Buy signals with a 90% confidence level.

Full Track Record

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Closing price (USD)
Buy signals

Forecast:

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3 Months
6 Months
1 Year

SEPN Average Past Performance & Win Rate

Three months after its 123 Buy signals since July 2026, SEPN had an average performance of xxxxxxx and a xxxxxx Win rate (positive performance).

123 Past SEPN Buy Signals	1 Month Later	3 Months Later	6 Months Later	1 Year Later
Average Performance				0.00%
Average Alpha				0.00%
Win Rate (% Positive Perf.)				0.00%
% Positive Alpha				0.00%

SEPN Frequently Asked Questions

Will Septerna stock go up?
According to Danelfin AI, Septerna has today an AI Score of 7/10 (Buy rating), because its probability of beating the market in 3 months (60.00%) is +9.18% vs. the average probability (50.82%) of all US-listed stocks.
What is the target price for Septerna stock?
Is it a good time to buy, sell, or hold Septerna stock right now?
Is Septerna undervalued right now?
What was the price range of Septerna stock over the past 12 months?
What is going on with Septerna stock in the last 3 months?
Does Septerna offer dividend payments?
What is the current market capitalization of Septerna?
When is the next SEPN earnings report date?

Septerna Inc Company Profile

Septerna Inc (SEPN) is a biotechnology company focused on developing novel therapeutics. It leverages a deep understanding of G protein-coupled receptors (GPCRs) to address diseases with significant unmet medical needs. The company aims to provide innovative treatment options for patients and healthcare providers by targeting these crucial cellular signaling proteins.

Septerna's core domain is drug discovery and development, specifically centered on GPCRs. These receptors are critical targets for many existing medicines. However, a substantial number remain undrugged or inadequately targeted due to their complex biology. The company employs a proprietary drug discovery platform designed to unlock the therapeutic potential of these challenging targets. This platform integrates advanced computational methods with experimental biology, including high-throughput screening, to identify and validate novel GPCR modulators.

The platform facilitates the creation of small molecule therapeutics. These molecules are engineered to precisely interact with specific GPCRs. This approach aims for improved efficacy and safety profiles compared to conventional methods. Septerna's research efforts concentrate on advancing a pipeline of drug candidates across various therapeutic areas. These areas include oncology and immunology, where the company seeks to address complex diseases by modulating specific GPCR pathways involved in disease progression.

The company focuses on progressing its candidates through preclinical and clinical stages of development. The ultimate goal is to bring new medicines to market. Septerna collaborates with academic institutions and pharmaceutical partners to accelerate its programs and expand its reach. Its potential future customers include patients, healthcare systems, and medical professionals globally. The company's revenue model is based on potential future product sales, milestone payments from collaborations, and licensing agreements, distributed directly and through strategic partnerships, with a global presence.

Sector:
Country:United States
Industry:
Address:250 East Grand Avenue, Suite 65, South San Francisco

Pros

Broad therapeutic applicability of GPCR targets

Proprietary drug discovery platform technology

High switching costs for established therapeutic regimens

Potential for multiple drug candidates from platform

Intellectual property protection for novel compounds

Cons

Extremely high capital intensity for drug development

Low probability of clinical trial success

Lengthy and uncertain regulatory approval processes

Long development timelines to market entry

Exposure to patent expiration and generic competition

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SEPN Stock AI Analysis

Septerna Inc

SEPN Stock AI Analysis

Septerna Inc

SEPN AI-Powered Stock Analysis

AI Score Explanation

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AI Score Explanation

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AI Score Alpha Factors

Alpha Signals: What Drives the AI Score

SEPN probability advantage of beating the market (3M): +9.18%

SEPN Trading Parameters

SEPN Proven Buy Signal & Price Forecast

SEPN Average Past Performance & Win Rate

SEPN Frequently Asked Questions

Will Septerna stock go up?

What is the target price for Septerna stock?

Is it a good time to buy, sell, or hold Septerna stock right now?

Is Septerna undervalued right now?

What was the price range of Septerna stock over the past 12 months?

What is going on with Septerna stock in the last 3 months?

Does Septerna offer dividend payments?

What is the current market capitalization of Septerna?

When is the next SEPN earnings report date?

Septerna Inc Company Profile

Pros

Cons

Pros

Cons

SEPN Company Profile Summary

SEPN Related Investment Themes

SEPN Related Stocks

SEPN Top 10 Industry Stocks

Pharmaceuticals

SEPN Top 10 Sector Stocks

Health Care

SEPN Stock AI Analysis

Septerna Inc

NASDAQ NMS - GLOBAL MARKET

Will Septerna stock go up?

What is the target price for Septerna stock?

Is it a good time to buy, sell, or hold Septerna stock right now?

Is Septerna undervalued right now?

What was the price range of Septerna stock over the past 12 months?

What is going on with Septerna stock in the last 3 months?

Does Septerna offer dividend payments?

What is the current market capitalization of Septerna?

When is the next SEPN earnings report date?

Pros

Cons

AI Score Explanation

Generating AI Score explanation

NASDAQ NMS - GLOBAL MARKET

SEPN Proven Buy Signal & Price Forecast